6FQX

Plasmodium falciparum 6-phosphogluconate dehydrogenase in its apo form, in complex with its cofactor NADP+ and in complex with its substrate 6-phosphogluconate

Summary for 6FQX

• Entry DOI: 10.2210/pdb6fqx/pdb
• Related: 6FQY 6FQZ
• Descriptor: 6-phosphogluconate dehydrogenase, decarboxylating, GLYCEROL, DI(HYDROXYETHYL)ETHER, ... (6 entities in total)
• Functional Keywords: plasmodium, complex, substrate, redoxregulation, oxidoreductase
• Biological source: Plasmodium falciparum 3D7
• Total number of polymer chains: 8
• Total formula weight: 427125.92

Authors

Fritz-Wolf, K.,Haeussler, K.,Reichmann, M.,Rahlfs, S.,Becker, K. (deposition date: 2018-02-15, release date: 2018-08-22, Last modification date: 2024-01-17)

• Primary citation: Haeussler, K.,Fritz-Wolf, K.,Reichmann, M.,Rahlfs, S.,Becker, K.; Characterization of Plasmodium falciparum 6-Phosphogluconate Dehydrogenase as an Antimalarial Drug Target.; J. Mol. Biol., 430:4049-4067, 2018; PubMed: 30098336; DOI: 10.1016/j.jmb.2018.07.030

Experimental method

X-RAY DIFFRACTION (2.8 Å)