6FQJ

GluA2(flop) G724C ligand binding core dimer bound to ZK200775 at 2.50 Angstrom resolution

6FQJ の概要

• エントリーDOI: 10.2210/pdb6fqj/pdb
• 分子名称: Glutamate receptor 2,Glutamate receptor 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid (3 entities in total)
• 機能のキーワード: ampar receptor, ligand binding domain, competitive antagonist, cross-linked dimer, membrane protein
• 由来する生物種: Rattus norvegicus (Rat); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 237872.64

構造登録者

Coombs, I.D.,Soto, D.,Gold, M.G.,Farrant, M.F.,Cull-Candy, S.G. (登録日: 2018-02-14, 公開日: 2019-03-13, 最終更新日: 2024-01-17)

• 主引用文献: Coombs, I.D.,Soto, D.,McGee, T.P.,Gold, M.G.,Farrant, M.,Cull-Candy, S.G.; Homomeric GluA2(R) AMPA receptors can conduct when desensitized.; Nat Commun, 10:4312-4312, 2019; PubMed: 31541113; DOI: 10.1038/s41467-019-12280-9

実験手法

X-RAY DIFFRACTION (2.50001683981 Å)