6FLM
Crystal structure of the human TRIM25 PRYSPRY domain
Summary for 6FLM
Entry DOI | 10.2210/pdb6flm/pdb |
Descriptor | E3 ubiquitin/ISG15 ligase TRIM25, SULFATE ION, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | pryspry domain, trim protein, e3 ligase, protein binding |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : Q14258 |
Total number of polymer chains | 3 |
Total formula weight | 69369.84 |
Authors | Cusack, S.,Kowalinski, E. (deposition date: 2018-01-26, release date: 2018-05-23, Last modification date: 2024-05-08) |
Primary citation | Koliopoulos, M.G.,Lethier, M.,van der Veen, A.G.,Haubrich, K.,Hennig, J.,Kowalinski, E.,Stevens, R.V.,Martin, S.R.,Reis E Sousa, C.,Cusack, S.,Rittinger, K. Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition. Nat Commun, 9:1820-1820, 2018 Cited by PubMed: 29739942DOI: 10.1038/s41467-018-04214-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.009 Å) |
Structure validation
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