6FIW

Human cytosolic 5'-nucleotidase II co-crystallized with 10mM Sodium ((4-(3'-((7H-purin-6-yl)carbamoyl)-[1,1'-biphenyl]-3-yl)-1H-imidazol-1-yl) methyl) phosphonate

Summary for 6FIW

Entry DOI	10.2210/pdb6fiw/pdb
Related	2J2C 4H4B 5CQZ 5CR7 6FIR 6FIS 6FIU
Descriptor	Cytosolic purine 5'-nucleotidase, SULFATE ION, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	62548.41
Authors	Aghajari, N.,Preeti, P. (deposition date: 2018-01-19, release date: 2019-01-30, Last modification date: 2019-03-06)
Primary citation	Guillon, R.,Rahimova, R.,Egron, D.,Rouanet, S.,Dumontet, C.,Aghajari, N.,Jordheim, L.P.,Chaloin, L.,Peyrottes, S. Lead optimization and biological evaluation of fragment-based cN-II inhibitors. Eur J Med Chem, 168:28-44, 2019 Cited by PubMed: 30798051 DOI: 10.1016/j.ejmech.2019.02.040 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation