5CQZ
Human cytosolic 5'-nucleotidase II in complex with 3-(3-Imidazol-1-ylphenyl)-N-(9H-purin-6-yl)benzamide
Summary for 5CQZ
Entry DOI | 10.2210/pdb5cqz/pdb |
Related | 4H4B |
Descriptor | Cytosolic purine 5'-nucleotidase, GLYCEROL, SULFATE ION, ... (6 entities in total) |
Functional Keywords | high km 5-prime nucleotidase, cn-ii, nucleotide-binding, phosphoprotein, hydrolase-hydrolase effector complex, hydrolase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: P49902 |
Total number of polymer chains | 2 |
Total formula weight | 130140.69 |
Authors | Preeti, P.,Aghajari, N. (deposition date: 2015-07-22, release date: 2015-12-23, Last modification date: 2024-05-08) |
Primary citation | Marton, Z.,Guillon, R.,Krimm, I.,Rahimova, R.,Egron, D.,Jordheim, L.P.,Aghajari, N.,Dumontet, C.,Perigaud, C.,Lionne, C.,Peyrottes, S.,Chaloin, L. Identification of Noncompetitive Inhibitors of Cytosolic 5'-Nucleotidase II Using a Fragment-Based Approach. J.Med.Chem., 58:9680-9696, 2015 Cited by PubMed: 26599519DOI: 10.1021/acs.jmedchem.5b01616 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
Download full validation report