5CQZ

Human cytosolic 5'-nucleotidase II in complex with 3-(3-Imidazol-1-ylphenyl)-N-(9H-purin-6-yl)benzamide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Cytosolic purine 5'-nucleotidase	polymer	555	64088.9	2	UniProt (P49902) Pfam (PF05761)	Homo sapiens (Human)	Cytosolic 5'-nucleotidase II
2	C, D, O, P (A, B)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
3	E, F, G, H, I... (A, B)	SULFATE ION	non-polymer		96.1	11	Chemie (SO4)
4	L, M, U, V (A, B)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
5	N, W (A, B)	1-(biphenyl-3-yl)-1H-imidazole	non-polymer		220.3	2	Chemie (53O)
6	X, Y (A, B)	water	water		18.0	80	Chemie (HOH)

Sequence modifications

A, B: 1 - 536 (UniProt: P49902)

PDB	External Database	Details
Met -18	-	initiating methionine
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Leu -5	-	expression tag
Val -4	-	expression tag
Pro -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	128177.9
Non-Polymers*	Number of molecules	21
	Total formula weight	1962.8
All*	Total formula weight	130140.7

*Water molecules are not included.