6FIR
Human cytosolic 5'-nucleotidase II soaked with 5mM3-Phenyl-N-(9H-purin-6-yl)benzamide
Summary for 6FIR
Entry DOI | 10.2210/pdb6fir/pdb |
Related | 2J2C 4H4B 5CQZ 5CR7 |
Descriptor | Cytosolic purine 5'-nucleotidase, MAGNESIUM ION, SULFATE ION, ... (5 entities in total) |
Functional Keywords | hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 65046.08 |
Authors | Aghajari, N.,Preeti, P. (deposition date: 2018-01-19, release date: 2019-01-30, Last modification date: 2024-01-17) |
Primary citation | Guillon, R.,Rahimova, R.,Egron, D.,Rouanet, S.,Dumontet, C.,Aghajari, N.,Jordheim, L.P.,Chaloin, L.,Peyrottes, S. Lead optimization and biological evaluation of fragment-based cN-II inhibitors. Eur J Med Chem, 168:28-44, 2019 Cited by PubMed: 30798051DOI: 10.1016/j.ejmech.2019.02.040 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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