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6FI4

Crystal structure of C-terminal modified Tau peptide-hybrid 3.2e with 14-3-3sigma

Summary for 6FI4
Entry DOI10.2210/pdb6fi4/pdb
Related6FAU 6FAV 6FAW 6FBW 6FBY
Descriptor14-3-3 protein sigma, PRO-SEP-LEU-PRO-DVA, CALCIUM ION, ... (7 entities in total)
Functional Keywordstau 14-3-3 alzheimer, structural protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight27470.36
Authors
Andrei, S.A.,Meijer, F.A.,Ottmann, C.,Milroy, L.G. (deposition date: 2018-01-17, release date: 2018-05-16, Last modification date: 2024-01-17)
Primary citationAndrei, S.A.,Meijer, F.A.,Neves, J.F.,Brunsveld, L.,Landrieu, I.,Ottmann, C.,Milroy, L.G.
Inhibition of 14-3-3/Tau by Hybrid Small-Molecule Peptides Operating via Two Different Binding Modes.
ACS Chem Neurosci, 9:2639-2654, 2018
Cited by
PubMed: 29722962
DOI: 10.1021/acschemneuro.8b00118
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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