6FI4
Crystal structure of C-terminal modified Tau peptide-hybrid 3.2e with 14-3-3sigma
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | 14-3-3 protein sigma | polymer | 236 | 26542.9 | 1 | UniProt (P31947) Pfam (PF00244) In PDB | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B | PRO-SEP-LEU-PRO-DVA | polymer | 5 | 591.6 | 1 | UniProt (by SIFTS) (P10636) In PDB | Homo sapiens | |
| 3 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | B | (2~{S})-2-(diphenylmethyl)pyrrolidine | non-polymer | 237.3 | 1 | Chemie (60H) | |||
| 7 | water | water | 18.0 | 133 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27134.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 335.9 | |
| All* | Total formula weight | 27470.4 |
