6FDQ

Structure of Chlamydia trachomatis effector protein Cdu1 bound to Compound 5

Summary for 6FDQ

• Entry DOI: 10.2210/pdb6fdq/pdb
• Related: 6FDK
• Descriptor: Deubiquitinase and deneddylase Dub1, N-benzyl-2-[(Z)-iminomethyl]pyrimidine-5-carboxamide (3 entities in total)
• Functional Keywords: chladub1, ce protease, dub, ubiquitin, covalent inhibitor., hydrolase
• Biological source: Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)
• Total number of polymer chains: 2
• Total formula weight: 61549.23

Authors

Ramirez, Y.,Kisker, C.,Altmann, E. (deposition date: 2017-12-26, release date: 2018-08-15, Last modification date: 2024-01-17)

• Primary citation: Ramirez, Y.A.,Adler, T.B.,Altmann, E.,Klemm, T.,Tiesmeyer, C.,Sauer, F.,Kathman, S.G.,Statsyuk, A.V.,Sotriffer, C.,Kisker, C.; Structural Basis of Substrate Recognition and Covalent Inhibition of Cdu1 from Chlamydia trachomatis.; ChemMedChem, 13:2014-2023, 2018; PubMed: 30028574; DOI: 10.1002/cmdc.201800364

Experimental method

X-RAY DIFFRACTION (2.3 Å)