6FBY
Crystal structure of C-terminal modified Tau peptide-hybrid 4.2b with 14-3-3sigma
Summary for 6FBY
Entry DOI | 10.2210/pdb6fby/pdb |
Related | 6FAU 6FAV 6FAW 6FBW |
Descriptor | 14-3-3 protein sigma, ACE-ARG-THR-PRO-SEP-LEU-PRO-GLY, THR-PRO-SEP-LEU-PRO-GLY, ... (7 entities in total) |
Functional Keywords | tau 14-3-3 alzheimer, structural protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 55235.89 |
Authors | Andrei, S.A.,Meijer, F.A.,Ottmann, C.,Milroy, L.G. (deposition date: 2017-12-20, release date: 2018-05-16, Last modification date: 2019-02-27) |
Primary citation | Andrei, S.A.,Meijer, F.A.,Neves, J.F.,Brunsveld, L.,Landrieu, I.,Ottmann, C.,Milroy, L.G. Inhibition of 14-3-3/Tau by Hybrid Small-Molecule Peptides Operating via Two Different Binding Modes. ACS Chem Neurosci, 9:2639-2654, 2018 Cited by PubMed: 29722962DOI: 10.1021/acschemneuro.8b00118 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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