6F7C
TUBULIN-Compound 12 complex
Summary for 6F7C
Entry DOI | 10.2210/pdb6f7c/pdb |
Descriptor | Tubulin alpha-1B chain, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (12 entities in total) |
Functional Keywords | cell cycle, tubulin fold, cytoskeleton, microtubule |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 6 |
Total formula weight | 264870.68 |
Authors | Muehlethaler, T.,Prota, A.E.,Steinmetz, M.O. (deposition date: 2017-12-08, release date: 2018-12-19, Last modification date: 2024-01-17) |
Primary citation | Cury, N.M.,Muhlethaler, T.,Laranjeira, A.B.A.,Canevarolo, R.R.,Zenatti, P.P.,Lucena-Agell, D.,Barasoain, I.,Song, C.,Sun, D.,Dovat, S.,Yunes, R.A.,Prota, A.E.,Steinmetz, M.O.,Diaz, J.F.,Yunes, J.A. Structural Basis of Colchicine-Site targeting Acylhydrazones active against Multidrug-Resistant Acute Lymphoblastic Leukemia. Iscience, 21:95-109, 2019 Cited by PubMed: 31655259DOI: 10.1016/j.isci.2019.10.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.002 Å) |
Structure validation
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