6F5F
Structure of ARTD2/PARP2 WGR domain bound to double strand DNA with 5 nucleotide overhang and 5'phosphate
Summary for 6F5F
Entry DOI | 10.2210/pdb6f5f/pdb |
Descriptor | Poly [ADP-ribose] polymerase 2, DNA (5'-D(P*CP*GP*GP*TP*CP*GP*CP*CP*TP*AP*TP*AP*GP*GP*C)-3') (2 entities in total) |
Functional Keywords | adp-ribosylation, dna repair, dna end joining, artd2, non-phosphorylated dna, dna binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 79444.61 |
Authors | Obaji, E.,Haikarainen, T.,Lehtio, L. (deposition date: 2017-12-01, release date: 2018-10-10, Last modification date: 2024-01-17) |
Primary citation | Obaji, E.,Haikarainen, T.,Lehtio, L. Structural basis for DNA break recognition by ARTD2/PARP2. Nucleic Acids Res., 46:12154-12165, 2018 Cited by PubMed: 30321391DOI: 10.1093/nar/gky927 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.98 Å) |
Structure validation
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