6F3P

Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa in complex with 3'-deoxyadenosine and K+ cation

Summary for 6F3P

• Entry DOI: 10.2210/pdb6f3p/pdb
• Descriptor: Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 3'-DEOXYADENOSINE, ... (7 entities in total)
• Functional Keywords: regulation of sam-dependent methylation reactions, hydrolase
• Biological source: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
• Total number of polymer chains: 2
• Total formula weight: 105638.44

Authors

Czyrko, J.,Brzezinski, K. (deposition date: 2017-11-28, release date: 2018-08-08, Last modification date: 2024-01-17)

• Primary citation: Czyrko, J.,Sliwiak, J.,Imiolczyk, B.,Gdaniec, Z.,Jaskolski, M.,Brzezinski, K.; Metal-cation regulation of enzyme dynamics is a key factor influencing the activity of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa.; Sci Rep, 8:11334-11334, 2018; PubMed: 30054521; DOI: 10.1038/s41598-018-29535-y

Experimental method

X-RAY DIFFRACTION (1.35 Å)