6F2N

Crystal structure of BCII Metallo-beta-lactamase in complex with KDU197

Summary for 6F2N

Entry DOI	10.2210/pdb6f2n/pdb
Related	5JMX 6EUM 6EW3 6EWE
Descriptor	Metallo-beta-lactamase type 2, ZINC ION, SULFATE ION, ... (5 entities in total)
Functional Keywords	antimicrobial resistance, metallo beta lactamase, inhibitor, hydrolase
Biological source	Bacillus cereus
Total number of polymer chains	1
Total formula weight	25542.82
Authors	McDonough, M.A.,El-Hussein, A.,Schofield, C.J.,Zhang, D.,Brem, J. (deposition date: 2017-11-24, release date: 2018-10-03, Last modification date: 2024-01-17)
Primary citation	Zhang, D.,Markoulides, M.S.,Stepanovs, D.,Rydzik, A.M.,El-Hussein, A.,Bon, C.,Kamps, J.J.A.G.,Umland, K.D.,Collins, P.M.,Cahill, S.T.,Wang, D.Y.,von Delft, F.,Brem, J.,McDonough, M.A.,Schofield, C.J. Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-beta-lactamases. Bioorg. Med. Chem., 26:2928-2936, 2018 Cited by PubMed: 29655609 DOI: 10.1016/j.bmc.2018.02.043 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.149 Å)

Structure validation