6EWX
Structure of Pragmin pseudo-kinase reveals a dimerization mechanism to regulate protein tyrosine phosphorylation and nuclear transcription
Summary for 6EWX
| Entry DOI | 10.2210/pdb6ewx/pdb |
| Descriptor | PEAK1-related kinase-activating pseudokinase 1, SULFATE ION (3 entities in total) |
| Functional Keywords | pseudokinase, cancer, scaffolding protein, cell invasion |
| Biological source | Rattus norvegicus (Rat) |
| Total number of polymer chains | 2 |
| Total formula weight | 107921.55 |
| Authors | Gelin, M.,Allemand, F.,Fournet, A.,Labesse, G. (deposition date: 2017-11-06, release date: 2018-01-31, Last modification date: 2018-04-18) |
| Primary citation | Lecointre, C.,Simon, V.,Kerneur, C.,Allemand, F.,Fournet, A.,Montarras, I.,Pons, J.L.,Gelin, M.,Brignatz, C.,Urbach, S.,Labesse, G.,Roche, S. Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation. Structure, 26:545-554.e4, 2018 Cited by PubMed: 29503074DOI: 10.1016/j.str.2018.01.017 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.771 Å) |
Structure validation
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