6EVK
Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter and cap analogue m7GTP
Summary for 6EVK
Entry DOI | 10.2210/pdb6evk/pdb |
Descriptor | Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2, ... (9 entities in total) |
Functional Keywords | influenza virus, rna-dependent rna polymerase, cap analogue, viral protein |
Biological source | Influenza A virus (A/little yellow-shouldered bat/Guatemala/060/2010(H17N10)) More |
Cellular location | Host nucleus : H6QM90 |
Total number of polymer chains | 5 |
Total formula weight | 277030.17 |
Authors | Pflug, A.,Cusack, S. (deposition date: 2017-11-01, release date: 2017-12-13, Last modification date: 2024-01-17) |
Primary citation | Pflug, A.,Gaudon, S.,Resa-Infante, P.,Lethier, M.,Reich, S.,Schulze, W.M.,Cusack, S. Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors. Nucleic Acids Res., 46:956-971, 2018 Cited by PubMed: 29202182DOI: 10.1093/nar/gkx1210 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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