6EVK

Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter and cap analogue m7GTP

6EVK の概要

• エントリーDOI: 10.2210/pdb6evk/pdb
• 分子名称: Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2, ... (9 entities in total)
• 機能のキーワード: influenza virus, rna-dependent rna polymerase, cap analogue, viral protein
• 由来する生物種: Influenza A virus (A/little yellow-shouldered bat/Guatemala/060/2010(H17N10)); 詳細
• 細胞内の位置: Host nucleus : H6QM90
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 277030.17

構造登録者

Pflug, A.,Cusack, S. (登録日: 2017-11-01, 公開日: 2017-12-13, 最終更新日: 2024-01-17)

• 主引用文献: Pflug, A.,Gaudon, S.,Resa-Infante, P.,Lethier, M.,Reich, S.,Schulze, W.M.,Cusack, S.; Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.; Nucleic Acids Res., 46:956-971, 2018; PubMed: 29202182; DOI: 10.1093/nar/gkx1210

実験手法

X-RAY DIFFRACTION (2.9 Å)