6ETE

Crystal structure of KDM4D with tetrazolhydrazide compound 5

Summary for 6ETE

DescriptorLysine-specific demethylase 4D, ZINC ION, NICKEL (II) ION, ... (7 entities in total)
Functional Keywordskdm4d, ligand binding, tetrazolylhydrazide, tetrazole, inhibitor design, cancer, epigenetics, oxidoreductase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight40459.35
Authors
Malecki, P.H.,Weiss, M.S.,Heinemann, U.,Link, A. (deposition date: 2017-10-26, release date: 2019-02-20)
Primary citation
Malecki, P.H.,Link, A.,Weiss, M.S.,Heinemann, U.
Crystal structure of KDM4D with tetrazolylhydrazide ligand NR128
To be published,
Experimental method
X-RAY DIFFRACTION (1.468 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.16350 3.2% 1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6ete
no rotation
Molmil generated image of 6ete
rotated about x axis by 90°
Molmil generated image of 6ete
rotated about y axis by 90°