6ESU

Artificial imine reductase mutant S112A-N118P-K121A-S122M

Summary for 6ESU

• Entry DOI: 10.2210/pdb6esu/pdb
• Related: 6ESS
• Descriptor: Streptavidin, 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-[4-(2-azanylethylsulfamoyl)phenyl]pentanamide, IRIDIUM ION, ... (6 entities in total)
• Functional Keywords: streptavidin, beta-barrel, biotin-binding protein
• Biological source: Streptomyces avidinii
• Cellular location: Secreted: P22629
• Total number of polymer chains: 1
• Total formula weight: 18024.72

Authors

Hestericova, M.,Heinisch, T.,Alonso-Cotchico, L.,Marechal, J.-D.,Vidossich, P.,Ward, T.R. (deposition date: 2017-10-24, release date: 2018-01-03, Last modification date: 2024-01-17)

• Primary citation: Hestericova, M.,Heinisch, T.,Alonso-Cotchico, L.,Marechal, J.D.,Vidossich, P.,Ward, T.R.; Directed Evolution of an Artificial Imine Reductase.; Angew. Chem. Int. Ed. Engl., 57:1863-1868, 2018; PubMed: 29265726; DOI: 10.1002/anie.201711016

Experimental method

X-RAY DIFFRACTION (1.78 Å)