6ERV
Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp013
Summary for 6ERV
| Entry DOI | 10.2210/pdb6erv/pdb |
| Descriptor | cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total) |
| Functional Keywords | complex, peptidic ligand, transferase |
| Biological source | Cricetulus griseus (Chinese hamster) More |
| Total number of polymer chains | 2 |
| Total formula weight | 43285.10 |
| Authors | Mueller, J.M.,Heine, A.,Klebe, G. (deposition date: 2017-10-19, release date: 2018-10-31, Last modification date: 2024-11-06) |
| Primary citation | Mueller, J.M.,Kirschner, R.,Geyer, A.,Klebe, G. Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage Acs Omega, 2019 Cited by DOI: 10.1021/acsomega.8b02364PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.06 Å) |
Structure validation
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