6EQ9

Crystal structure of JNK3 in complex with AMP-PCP

Summary for 6EQ9

Entry DOI	10.2210/pdb6eq9/pdb
Descriptor	Mitogen-activated protein kinase 10, MAGNESIUM ION, SODIUM ION, ... (9 entities in total)
Functional Keywords	protein kinase activiy map kinase activity atp binding protein phosphorylation, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	86370.91
Authors	Macedo, J.T.,Stehle, T.,Blaum, B.S. (deposition date: 2017-10-12, release date: 2018-08-08, Last modification date: 2024-01-17)
Primary citation	Ansideri, F.,Macedo, J.T.,Eitel, M.,El-Gokha, A.,Zinad, D.S.,Scarpellini, C.,Kudolo, M.,Schollmeyer, D.,Boeckler, F.M.,Blaum, B.S.,Laufer, S.A.,Koch, P. Structural Optimization of a Pyridinylimidazole Scaffold: Shifting the Selectivity from p38 alpha Mitogen-Activated Protein Kinase to c-Jun N-Terminal Kinase 3. ACS Omega, 3:7809-7831, 2018 Cited by PubMed: 30087925 DOI: 10.1021/acsomega.8b00668 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.83 Å)

Structure validation