Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004707 | molecular_function | MAP kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
B | 0004672 | molecular_function | protein kinase activity |
B | 0004707 | molecular_function | MAP kinase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | binding site for residue MG A 501 |
Chain | Residue |
A | GLN75 |
A | ASP207 |
A | ACP505 |
A | HOH654 |
A | HOH738 |
site_id | AC2 |
Number of Residues | 6 |
Details | binding site for residue NA A 502 |
Chain | Residue |
A | ILE124 |
A | HOH693 |
A | VAL118 |
A | ASN119 |
A | HIS120 |
A | ILE123 |
site_id | AC3 |
Number of Residues | 5 |
Details | binding site for residue NA A 503 |
Chain | Residue |
A | ILE276 |
A | THR281 |
A | PRO302 |
A | HOH717 |
A | HOH722 |
site_id | AC4 |
Number of Residues | 1 |
Details | binding site for residue BME A 504 |
site_id | AC5 |
Number of Residues | 24 |
Details | binding site for residue ACP A 505 |
Chain | Residue |
A | ILE70 |
A | GLY71 |
A | GLY73 |
A | ALA74 |
A | GLN75 |
A | GLY76 |
A | ALA91 |
A | LYS93 |
A | MET146 |
A | GLU147 |
A | MET149 |
A | ASN152 |
A | LYS191 |
A | SER193 |
A | ASN194 |
A | LEU206 |
A | ASP207 |
A | MG501 |
A | HOH654 |
A | HOH686 |
A | HOH716 |
A | HOH726 |
A | HOH738 |
A | HOH742 |
site_id | AC6 |
Number of Residues | 12 |
Details | binding site for residue C15 A 506 |
Chain | Residue |
A | GLY215 |
A | THR216 |
A | ILE235 |
A | LEU236 |
A | GLY237 |
A | GLY239 |
A | GLN291 |
A | VAL294 |
A | HOH681 |
B | GLU160 |
B | ASP162 |
B | ARG165 |
site_id | AC7 |
Number of Residues | 4 |
Details | binding site for residue PEG A 507 |
Chain | Residue |
A | ILE269 |
A | TYR297 |
B | ASP150 |
B | PEG503 |
site_id | AC8 |
Number of Residues | 5 |
Details | binding site for residue CL B 501 |
Chain | Residue |
A | HOH690 |
B | GLU242 |
B | ASN243 |
B | VAL350 |
B | HOH620 |
site_id | AC9 |
Number of Residues | 23 |
Details | binding site for residue ACP B 502 |
Chain | Residue |
B | ILE70 |
B | SER72 |
B | GLY73 |
B | ALA74 |
B | VAL78 |
B | ALA91 |
B | LYS93 |
B | ILE124 |
B | MET146 |
B | GLU147 |
B | MET149 |
B | ASN152 |
B | LYS191 |
B | SER193 |
B | ASN194 |
B | LEU206 |
B | ASP207 |
B | HOH619 |
B | HOH626 |
B | HOH631 |
B | HOH644 |
B | HOH659 |
B | HOH666 |
site_id | AD1 |
Number of Residues | 1 |
Details | binding site for residue PEG B 503 |
site_id | AD2 |
Number of Residues | 2 |
Details | binding site for residue PEG B 504 |
Chain | Residue |
B | ILE269 |
B | THR293 |
Functional Information from PROSITE/UniProt
site_id | PS00108 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IiHrDLKpsNIVV |
Chain | Residue | Details |
A | ILE185-VAL197 | |
site_id | PS01351 |
Number of Residues | 103 |
Details | MAPK MAP kinase signature. FqnqthakrayRElvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldhermsyllyqmlcgikhlhsagiih..........RDlKpsnivvksdC |
Chain | Residue | Details |
A | PHE99-CYS201 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Proton acceptor |
Chain | Residue | Details |
A | ASP189 | |
B | ASP189 | |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | BINDING: |
Chain | Residue | Details |
A | ILE70 | |
A | LYS93 | |
B | ILE70 | |
B | LYS93 | |
Chain | Residue | Details |
A | THR221 | |
B | THR221 | |
Chain | Residue | Details |
A | TYR223 | |
B | TYR223 | |