Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004707 | molecular_function | MAP kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004707 | molecular_function | MAP kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 501 |
| Chain | Residue |
| A | GLN75 |
| A | ASP207 |
| A | ACP505 |
| A | HOH654 |
| A | HOH738 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 502 |
| Chain | Residue |
| A | ILE124 |
| A | HOH693 |
| A | VAL118 |
| A | ASN119 |
| A | HIS120 |
| A | ILE123 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 503 |
| Chain | Residue |
| A | ILE276 |
| A | THR281 |
| A | PRO302 |
| A | HOH717 |
| A | HOH722 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue BME A 504 |
| site_id | AC5 |
| Number of Residues | 24 |
| Details | binding site for residue ACP A 505 |
| Chain | Residue |
| A | ILE70 |
| A | GLY71 |
| A | GLY73 |
| A | ALA74 |
| A | GLN75 |
| A | GLY76 |
| A | ALA91 |
| A | LYS93 |
| A | MET146 |
| A | GLU147 |
| A | MET149 |
| A | ASN152 |
| A | LYS191 |
| A | SER193 |
| A | ASN194 |
| A | LEU206 |
| A | ASP207 |
| A | MG501 |
| A | HOH654 |
| A | HOH686 |
| A | HOH716 |
| A | HOH726 |
| A | HOH738 |
| A | HOH742 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | binding site for residue C15 A 506 |
| Chain | Residue |
| A | GLY215 |
| A | THR216 |
| A | ILE235 |
| A | LEU236 |
| A | GLY237 |
| A | GLY239 |
| A | GLN291 |
| A | VAL294 |
| A | HOH681 |
| B | GLU160 |
| B | ASP162 |
| B | ARG165 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 507 |
| Chain | Residue |
| A | ILE269 |
| A | TYR297 |
| B | ASP150 |
| B | PEG503 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue CL B 501 |
| Chain | Residue |
| A | HOH690 |
| B | GLU242 |
| B | ASN243 |
| B | VAL350 |
| B | HOH620 |
| site_id | AC9 |
| Number of Residues | 23 |
| Details | binding site for residue ACP B 502 |
| Chain | Residue |
| B | ILE70 |
| B | SER72 |
| B | GLY73 |
| B | ALA74 |
| B | VAL78 |
| B | ALA91 |
| B | LYS93 |
| B | ILE124 |
| B | MET146 |
| B | GLU147 |
| B | MET149 |
| B | ASN152 |
| B | LYS191 |
| B | SER193 |
| B | ASN194 |
| B | LEU206 |
| B | ASP207 |
| B | HOH619 |
| B | HOH626 |
| B | HOH631 |
| B | HOH644 |
| B | HOH659 |
| B | HOH666 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue PEG B 503 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue PEG B 504 |
| Chain | Residue |
| B | ILE269 |
| B | THR293 |
Functional Information from PROSITE/UniProt
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IiHrDLKpsNIVV |
| Chain | Residue | Details |
| A | ILE185-VAL197 | |
| site_id | PS01351 |
| Number of Residues | 103 |
| Details | MAPK MAP kinase signature. FqnqthakrayRElvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldhermsyllyqmlcgikhlhsagiih..........RDlKpsnivvksdC |
| Chain | Residue | Details |
| A | PHE99-CYS201 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {} |
