6EP1
Transthyretin in complex with 5-(4-nitrophenylazo)-3-iodosalicylic acid
Summary for 6EP1
| Entry DOI | 10.2210/pdb6ep1/pdb |
| Related | 6EOY |
| Descriptor | Transthyretin, 5-(4-nitrophenylazo)-3-iodosalicylic acid (3 entities in total) |
| Functional Keywords | amyloid inhibitor, fap inhibitor, transthyretin, transport protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 26038.45 |
| Authors | Leite, J.P.,Gales, L. (deposition date: 2017-10-10, release date: 2018-10-31, Last modification date: 2024-01-17) |
| Primary citation | Leite, J.P.,Gales, L. Targeting transthyretin in Alzheimer's disease: Drug discovery of small-molecule chaperones as disease-modifying drug candidates for Alzheimer's disease Eur.J.Med.Chem., 2021 Cited by DOI: 10.1016/j.ejmech.2021.113847PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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