6EM7

Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp120 and ADP

6EM7 の概要

• エントリーDOI: 10.2210/pdb6em7/pdb
• 分子名称: cAMP-dependent protein kinase catalytic subunit alpha, UPF0418 protein FAM164A, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (6 entities in total)
• 機能のキーワード: complex, peptidic ligand, transferase
• 由来する生物種: Cricetulus griseus (Chinese hamster); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43873.60

構造登録者

Mueller, J.M.,Heine, A.,Klebe, G. (登録日: 2017-10-01, 公開日: 2018-10-10, 最終更新日: 2024-11-13)

• 主引用文献: Mueller, J.M.,Kirschner, R.,Geyer, A.,Klebe, G.; Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage; Acs Omega, 2019; DOI: 10.1021/acsomega.8b02364

実験手法

X-RAY DIFFRACTION (1.238 Å)