6EL8

Crystal structure of the Forkhead domain of human FOXN1 in complex with DNA

Summary for 6EL8

Related5OCN
DescriptorForkhead box protein N1, DNA (5'-D(*GP*GP*TP*GP*GP*CP*GP*TP*CP*TP*TP*CP*A)-3'), DNA (5'-D(*TP*GP*AP*AP*GP*AP*CP*GP*CP*CP*AP*CP*C)-3'), ... (4 entities in total)
Functional Keywordsfoxn1, thumus, transcription factor, structural genomics, structural genomics consortium, sgc, dna binding protein
Biological sourceHomo sapiens (Human)
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Cellular locationNucleus O15353
Total number of polymer chains6
Total molecular weight38937.17
Authors
Newman, J.A.,Aitkenhead, H.A.,Pinkas, D.M.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O.,Structural Genomics Consortium (SGC) (deposition date: 2017-09-28, release date: 2017-11-15, Last modification date: 2018-04-11)
Primary citation
Newman, J.A.,Aitkenhead, H.A.,Pinkas, D.M.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O.
Crystal structure of the Forkhead domain of human FOXN1 in complex with DNA
To be published,
Experimental method
X-RAY DIFFRACTION (1.61 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.241401.2%4.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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More Biological unit images

Molmil generated image of 6el8
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Molmil generated image of 6el8
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Molmil generated image of 6el8
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (6el8.pdb1.gz [29.65 KB])
Coordinate files for Biological unit (6el8.pdb2.gz [29.7 KB])