6EK0

High-resolution cryo-EM structure of the human 80S ribosome

This is a large structure.

Summary for 6EK0

EMDB information3883 4243 4244 4245 4263
Descriptor28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ... (86 entities in total)
Functional Keywordshuman 80s ribosome, rrna, rrna modifications, high-resolution cryo-em, ribosome
Biological sourceHomo sapiens (Human)
Total number of polymer chains81
Total molecular weight3842376.87
Authors
Natchiar, S.K.,Myasnikov, A.G.,Kratzat, H.,Hazemann, I.,Klaholz, B.P. (deposition date: 2017-09-24, release date: 2018-01-24, Last modification date: 2019-05-15)
Primary citation
Natchiar, S.K.,Myasnikov, A.G.,Kratzat, H.,Hazemann, I.,Klaholz, B.P.
Visualization of chemical modifications in the human 80S ribosome structure.
Nature, 551:472-477, 2017
PubMed: 29143818 (PDB entries with the same primary citation)
DOI: 10.1038/nature24482
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
?

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone4 0.3% 1.7% 0.43MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 6ek0
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Molmil generated image of 6ek0
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Molmil generated image of 6ek0
rotated about y axis by 90°