6EHG

complement component C3b in complex with a nanobody

6EHG の概要

• エントリーDOI: 10.2210/pdb6ehg/pdb
• 分子名称: Complement C3, hC3Nb1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: protein complex, inhibitor, complement, complement system, single domain antibody, nanobody, immune system
• 由来する生物種: Lama glama (llama); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 190536.01

構造登録者

Jensen, R.K.,Andersen, K.R.,Gadeberg, T.A.F.,Laursen, N.S.,Andersen, G.R. (登録日: 2017-09-13, 公開日: 2018-02-14, 最終更新日: 2024-01-17)

• 主引用文献: Jensen, R.K.,Pihl, R.,Gadeberg, T.A.F.,Jensen, J.K.,Andersen, K.R.,Thiel, S.,Laursen, N.S.,Andersen, G.R.; A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement.; J. Biol. Chem., 293:6269-6281, 2018; PubMed: 29497000; DOI: 10.1074/jbc.RA117.001179

実験手法

X-RAY DIFFRACTION (2.65 Å)