6EG8
Structure of the GDP-bound Gs heterotrimer
Summary for 6EG8
Entry DOI | 10.2210/pdb6eg8/pdb |
Descriptor | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... (6 entities in total) |
Functional Keywords | g protein heterotrimer gdp gpcr, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 361495.21 |
Authors | Hilger, D.,Liu, X.,Aschauer, P.,Kobilka, B.K. (deposition date: 2018-08-19, release date: 2019-06-05, Last modification date: 2024-03-13) |
Primary citation | Liu, X.,Xu, X.,Hilger, D.,Aschauer, P.,Tiemann, J.K.S.,Du, Y.,Liu, H.,Hirata, K.,Sun, X.,Guixa-Gonzalez, R.,Mathiesen, J.M.,Hildebrand, P.W.,Kobilka, B.K. Structural Insights into the Process of GPCR-G Protein Complex Formation. Cell, 177:1243-1251.e12, 2019 Cited by PubMed: 31080070DOI: 10.1016/j.cell.2019.04.021 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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