6EDZ
Crystal structure of Mycobacterium tuberculosis ICL2 in complex with acetyl-CoA, form I
Summary for 6EDZ
| Entry DOI | 10.2210/pdb6edz/pdb |
| Related | 6EDW 6EE1 |
| Descriptor | Isocitrate lyase 2, ACETYL COENZYME *A (3 entities in total) |
| Functional Keywords | lyase |
| Biological source | Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) |
| Total number of polymer chains | 4 |
| Total formula weight | 353702.19 |
| Authors | Bashiri, G.,Bhusal, R.,Leung, I. (deposition date: 2018-08-12, release date: 2019-08-14, Last modification date: 2019-10-23) |
| Primary citation | Bhusal, R.P.,Jiao, W.,Kwai, B.X.C.,Reynisson, J.,Collins, A.J.,Sperry, J.,Bashiri, G.,Leung, I.K.H. Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2. Nat Commun, 10:4639-4639, 2019 Cited by PubMed: 31604954DOI: 10.1038/s41467-019-12614-7 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.67 Å) |
Structure validation
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