6EA7

Structure of EBOV GPcl in complex with the pan-ebolavirus mAb ADI-15878

6EA7 の概要

• エントリーDOI: 10.2210/pdb6ea7/pdb
• 関連するPDBエントリー: 6EA5
• 分子名称: Envelope glycoprotein, ADI-15878 Fab Heavy Chain, ADI-15878 Fab Light Chain, ... (8 entities in total)
• 機能のキーワード: mab, gp, glycoprotein, ebola, ebov, antibody, bdbv, bundibugyo, neutralization, immune, bnab, complex, filovirus, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Ebola virus (ZEBOV); 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 239190.88

構造登録者

West, B.R.,Moyer, C.L.,King, L.B.,Fusco, M.L.,Milligan, J.C.,Hui, S.,Saphire, E.O. (登録日: 2018-08-02, 公開日: 2018-09-19, 最終更新日: 2023-10-11)

• 主引用文献: West, B.R.,Moyer, C.L.,King, L.B.,Fusco, M.L.,Milligan, J.C.,Hui, S.,Saphire, E.O.; Structural Basis of Pan-Ebolavirus Neutralization by a Human Antibody against a Conserved, yet Cryptic Epitope.; MBio, 9:-, 2018; PubMed: 30206174; DOI: 10.1128/mBio.01674-18

実験手法

X-RAY DIFFRACTION (4.25 Å)