6EA7

Structure of EBOV GPcl in complex with the pan-ebolavirus mAb ADI-15878

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (A, C, E)	Envelope glycoprotein	polymer	163	17778.2	3	UniProt (P87666) Pfam (PF01611) UniProt (by SIFTS) (Q05320)	Ebola virus (ZEBOV)	GP1,2,GP
2	B, D, F (B, D, F)	Envelope glycoprotein	polymer	111	12352.1	3	UniProt (O11457) Pfam (PF22307) UniProt (by SIFTS) (Q05320)	Ebola virus (ZEBOV)	GP1,2,GP
3	G, I, K (H, M, Q)	ADI-15878 Fab Heavy Chain	polymer	233	24743.6	3		Homo sapiens (Human)
4	H, J, L (L, N, R)	ADI-15878 Fab Light Chain	polymer	213	23093.5	3		Homo sapiens (Human)
5	M (G)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G21290RB)
6	N, O (I, J)	beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1479.3	2	In PDB GlyTouCan (G89993FE)
7	P (K)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1317.2	1	In PDB GlyTouCan (G39213VZ)
8	Q, R (C, E)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	233902.0
Branched	Number of molecules	4
	Total formula weight	4846.4
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	239190.9

*Water molecules are not included.