6E7M
Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:T51D:A28C mutant of human Cellular Retinol Binding Protein II
Summary for 6E7M
Entry DOI | 10.2210/pdb6e7m/pdb |
Descriptor | Retinol-binding protein 2, ACETATE ION, GLYCEROL, ... (5 entities in total) |
Functional Keywords | retinol, ilbp, protein switch, lipid binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 64005.65 |
Authors | Ghanbarpour, A.,Geiger, J. (deposition date: 2018-07-26, release date: 2019-10-16, Last modification date: 2023-10-11) |
Primary citation | Ghanbarpour, A.,Pinger, C.,Esmatpour Salmani, R.,Assar, Z.,Santos, E.M.,Nosrati, M.,Pawlowski, K.,Spence, D.,Vasileiou, C.,Jin, X.,Borhan, B.,Geiger, J.H. Engineering the hCRBPII Domain-Swapped Dimer into a New Class of Protein Switches. J.Am.Chem.Soc., 141:17125-17132, 2019 Cited by PubMed: 31557439DOI: 10.1021/jacs.9b04664 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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