6E68

NAMPT co-crystal with inhibitor compound 2

6E68 の概要

• エントリーDOI: 10.2210/pdb6e68/pdb
• 分子名称: Nicotinamide phosphoribosyltransferase, PHOSPHATE ION, (2E)-N-{4-[1-(3-aminobenzene-1-carbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamide, ... (4 entities in total)
• 機能のキーワード: nicotinamide phosphoribosyltransferase, cytotoxic, antibody-drug conjugates, anti-tumor, cytosolic protein, transferase-inhibitor complex, transferase/inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 109986.45

構造登録者

Waight, A.B.,Neumann, C.S. (登録日: 2018-07-24, 公開日: 2018-08-08, 最終更新日: 2023-10-11)

• 主引用文献: Neumann, C.S.,Olivas, K.C.,Anderson, M.E.,Cochran, J.H.,Jin, S.,Li, F.,Loftus, L.V.,Meyer, D.W.,Neale, J.,Nix, J.C.,Pittman, P.G.,Simmons, J.K.,Ulrich, M.L.,Waight, A.B.,Wong, A.,Zaval, M.C.,Zeng, W.,Lyon, R.P.,Senter, P.D.; NAMPT co-crystal with inhibitor compound 2; to be published,

実験手法

X-RAY DIFFRACTION (1.5 Å)