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6E67

Structure of beta2 adrenergic receptor fused to a Gs peptide

Summary for 6E67
Entry DOI10.2210/pdb6e67/pdb
DescriptorBeta-2 adrenergic receptor,Endolysin,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Beta-2 adrenergic receptor chimera, 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one (2 entities in total)
Functional Keywordsg protein coupled receptor, membrane protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight121057.96
Authors
Liu, X.,Xu, X.,Hilger, D.,Tiemann, J.,Liu, H.,Du, Y.,Hirata, K.,Sun, X.,Guixa-Gonzalez, R.,Mathiesen, J.,Hildebrand, P.,Kobilka, B. (deposition date: 2018-07-24, release date: 2019-06-05, Last modification date: 2023-10-11)
Primary citationLiu, X.,Xu, X.,Hilger, D.,Aschauer, P.,Tiemann, J.K.S.,Du, Y.,Liu, H.,Hirata, K.,Sun, X.,Guixa-Gonzalez, R.,Mathiesen, J.M.,Hildebrand, P.W.,Kobilka, B.K.
Structural Insights into the Process of GPCR-G Protein Complex Formation.
Cell, 177:1243-1251.e12, 2019
Cited by
PubMed: 31080070
DOI: 10.1016/j.cell.2019.04.021
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.7 Å)
Structure validation

217705

數據於2024-03-27公開中

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