6E67

Structure of beta2 adrenergic receptor fused to a Gs peptide

6E67 の概要

• エントリーDOI: 10.2210/pdb6e67/pdb
• 分子名称: Beta-2 adrenergic receptor,Endolysin,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Beta-2 adrenergic receptor chimera, 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one (2 entities in total)
• 機能のキーワード: g protein coupled receptor, membrane protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 121057.96

構造登録者

Liu, X.,Xu, X.,Hilger, D.,Tiemann, J.,Liu, H.,Du, Y.,Hirata, K.,Sun, X.,Guixa-Gonzalez, R.,Mathiesen, J.,Hildebrand, P.,Kobilka, B. (登録日: 2018-07-24, 公開日: 2019-06-05, 最終更新日: 2023-10-11)

• 主引用文献: Liu, X.,Xu, X.,Hilger, D.,Aschauer, P.,Tiemann, J.K.S.,Du, Y.,Liu, H.,Hirata, K.,Sun, X.,Guixa-Gonzalez, R.,Mathiesen, J.M.,Hildebrand, P.W.,Kobilka, B.K.; Structural Insights into the Process of GPCR-G Protein Complex Formation.; Cell, 177:1243-1251.e12, 2019; PubMed: 31080070; DOI: 10.1016/j.cell.2019.04.021

実験手法

X-RAY DIFFRACTION (3.7 Å)