6E1O
afTMEM16 reconstituted in nanodiscs in the presence of Ca2+ and ceramide 24:0
Summary for 6E1O
Entry DOI | 10.2210/pdb6e1o/pdb |
Related | 6DZ7 6E0H |
EMDB information | 8931 8948 8959 |
Descriptor | Plasma membrane channel protein (Aqy1), putative, CALCIUM ION, DODECANE, ... (6 entities in total) |
Functional Keywords | scramblase, ca2+-activated, membrane-reorganization, lipid transport |
Biological source | Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) |
Total number of polymer chains | 2 |
Total formula weight | 171722.61 |
Authors | Falzone, M.E.,Accardi, A. (deposition date: 2018-07-10, release date: 2019-02-06, Last modification date: 2024-03-13) |
Primary citation | Falzone, M.E.,Rheinberger, J.,Lee, B.C.,Peyear, T.,Sasset, L.,Raczkowski, A.M.,Eng, E.T.,Di Lorenzo, A.,Andersen, O.S.,Nimigean, C.M.,Accardi, A. Structural basis of Ca2+-dependent activation and lipid transport by a TMEM16 scramblase. Elife, 8:-, 2019 Cited by PubMed: 30648972DOI: 10.7554/eLife.43229 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.59 Å) |
Structure validation
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