6DZL

Ebola virus Makona variant GP (mucin-deleted) in complex with pan-ebolavirus human antibody ADI-15878 Fab

Summary for 6DZL

• Entry DOI: 10.2210/pdb6dzl/pdb
• EMDB information: 8935
• Descriptor: Ebola virus Makona GP1, Ebola virus Makona GP2, Fv domain of ADI-15878 Fab light chain, ... (7 entities in total)
• Functional Keywords: ebola, antibody, pan-ebolavirus, internal fusion loop, hr1, glycoprotein, viral protein
• Biological source: Zaire ebolavirus (ZEBOV); More
• Total number of polymer chains: 12
• Total formula weight: 240891.30

Authors

Murin, C.D.,Ward, A.B. (deposition date: 2018-07-05, release date: 2018-09-12, Last modification date: 2020-07-29)

• Primary citation: Murin, C.D.,Bruhn, J.F.,Bornholdt, Z.A.,Copps, J.,Stanfield, R.,Ward, A.B.; Structural Basis of Pan-Ebolavirus Neutralization by an Antibody Targeting the Glycoprotein Fusion Loop.; Cell Rep, 24:2723-2732.e4, 2018; PubMed: 30184505; DOI: 10.1016/j.celrep.2018.08.009

Experimental method

ELECTRON MICROSCOPY (4.14 Å)