6DWE

Crystal structure of tryptophan synthase from M. tuberculosis - aminoacrylate- and BRD0059-bound form

6DWE の概要

• エントリーDOI: 10.2210/pdb6dwe/pdb
• 分子名称: Tryptophan synthase alpha chain, 1,2-ETHANEDIOL, TRIETHYLENE GLYCOL, ... (12 entities in total)
• 機能のキーワード: plp, heterotetramer, amino acid biosynthesis, substrate channeling, allostery, structural genomics, center for structural genomics of infectious diseases, csgid, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 293915.00

構造登録者

Chang, C.,Michalska, K.,Maltseva, N.I.,Jedrzejczak, R.,McCarren, P.,Nag, P.P.,Joachimiak, A.,Satchell, K.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2018-06-26, 公開日: 2018-07-11, 最終更新日: 2023-10-11)

• 主引用文献: Chang, C.,Michalska, K.,Maltseva, N.I.,Jedrzejczak, R.,McCarren, P.,Nag, P.P.,Joachimiak, A.,Satchell, K.; Crystal structure of tryptophan synthase from M. tuberculosis - closed form with BRD6309 bound; To be Published,

実験手法

X-RAY DIFFRACTION (2.691 Å)