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6DPH

Crystal Structure of Bacillus Halodurans Ribonuclease H1 E188A in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mn2+ and 200 mM K+ for 120 s at 21 C

Summary for 6DPH
Entry DOI10.2210/pdb6dph/pdb
Group depositionCleavage of RNA by B. Halodurans Ribonuclease H1 (G_1001001)
DescriptorRibonuclease H, 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of intact RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), ... (11 entities in total)
Functional Keywordsprotein-rna-dna complex, double helix, rna hydrolysis, in crystallo catalysis, metal dependent catalysis, monovalent cations, divalent cations, hydrolase-rna-dna complex, hydrolase/rna/dna
Biological sourceBacillus halodurans
More
Total number of polymer chains4
Total formula weight21305.16
Authors
Samara, N.L.,Yang, W. (deposition date: 2018-06-09, release date: 2018-08-15, Last modification date: 2023-10-11)
Primary citationSamara, N.L.,Yang, W.
Cation trafficking propels RNA hydrolysis.
Nat. Struct. Mol. Biol., 25:715-721, 2018
Cited by
PubMed: 30076410
DOI: 10.1038/s41594-018-0099-4
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.339 Å)
Structure validation

217705

数据于2024-03-27公开中

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