6DNK
Human Stimulator of Interferon Genes
Summary for 6DNK
Entry DOI | 10.2210/pdb6dnk/pdb |
Descriptor | Stimulator of interferon genes protein, cGAMP (3 entities in total) |
Functional Keywords | human sting, complex, 2', 3'-cgamp, tmem173, ala230 allelle, 230a/232r, immune system |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 21772.13 |
Authors | Fernandez, D.,Li, L.,Ergun, S.L. (deposition date: 2018-06-06, release date: 2019-03-13, Last modification date: 2023-10-11) |
Primary citation | Ergun, S.L.,Fernandez, D.,Weiss, T.M.,Li, L. STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition. Cell, 178:290-301.e10, 2019 Cited by PubMed: 31230712DOI: 10.1016/j.cell.2019.05.036 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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