6DFY
Remodeled crystal structure of DNA-bound DUX4-HD2
Summary for 6DFY
Entry DOI | 10.2210/pdb6dfy/pdb |
Descriptor | Double homeobox protein 4, DNA (5'-D(*AP*AP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*GP*T)-3'), DNA (5'-D(*TP*TP*CP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*A)-3'), ... (4 entities in total) |
Functional Keywords | dux4-responsive-element, dna binding protein, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 23129.23 |
Authors | Aihara, H.,Shi, K. (deposition date: 2018-05-15, release date: 2018-09-05, Last modification date: 2023-10-11) |
Primary citation | Aihara, H.,Shi, K.,Lee, J.K.,Bosnakovski, D.,Kyba, M. Comment on structural basis of DUX4/IGH-driven transactivation. Leukemia, 32:2090-2092, 2018 Cited by PubMed: 30054554DOI: 10.1038/s41375-018-0217-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.623 Å) |
Structure validation
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