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6DCU

Crystal structure of PPAR gamma co-crystallized with nTZDpa

Summary for 6DCU
Entry DOI10.2210/pdb6dcu/pdb
DescriptorPeroxisome proliferator-activated receptor gamma, 5-CHLORO-1-(4-CHLOROBENZYL)-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID (2 entities in total)
Functional Keywordsnuclear receptor, transcription factor, super agonist, ligand binding domain, coactivator, med1, dna binding protein, dna binding protein-agonist complex, dna binding protein/agonist
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total formula weight70094.69
Authors
Mou, T.C.,Chrisman, I.M.,Hughes, T.S.,Sprang, S.R. (deposition date: 2018-05-08, release date: 2019-05-15, Last modification date: 2023-10-11)
Primary citationMou, T.C.,Chrisman, I.M.,Hughes, T.S.,Sprang, S.R.
Crystal structure of PPAR gamma in complex with NMP422
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.95 Å)
Structure validation

217705

건을2024-03-27부터공개중

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