6DCC
Structure of methylphosphate capping enzyme methyltransferase domain in complex with 5' end of 7SK RNA
Summary for 6DCC
Entry DOI | 10.2210/pdb6dcc/pdb |
Descriptor | 7SK snRNA methylphosphate capping enzyme, human 7SK RNA stem-loop 1 proximal methylated, S-ADENOSYL-L-HOMOCYSTEINE, ... (5 entities in total) |
Functional Keywords | rna methyl transferase, mepce, 7sk rna, transferase-rna complex, transferase/rna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 47327.12 |
Authors | Yang, Y.,Eichhorn, C.,Cascio, D.,Feigon, J. (deposition date: 2018-05-04, release date: 2018-12-19, Last modification date: 2023-10-11) |
Primary citation | Yang, Y.,Eichhorn, C.D.,Wang, Y.,Cascio, D.,Feigon, J. Structural basis of 7SK RNA 5'-gamma-phosphate methylation and retention by MePCE. Nat. Chem. Biol., 15:132-140, 2019 Cited by PubMed: 30559425DOI: 10.1038/s41589-018-0188-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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