6DCC
Structure of methylphosphate capping enzyme methyltransferase domain in complex with 5' end of 7SK RNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 7SK snRNA methylphosphate capping enzyme | polymer | 309 | 35122.8 | 1 | UniProt (Q7L2J0) Pfam (PF06859) | Homo sapiens (Human) | MePCE,Bicoid-interacting protein 3 homolog,Bin3 homolog |
| 2 | B (B) | human 7SK RNA stem-loop 1 proximal methylated | polymer | 36 | 11723.9 | 1 | Homo sapiens | ||
| 3 | C (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (25210495) PubChem (13792) PubChem (177678424) PubChem (44361184) PubChem (21125603) PubChem (46936206) PubChem (50989525) PubChem (25203782) PubChem (51380914) PubChem (52224398) PubChem (189149) PubChem (57544532) PubChem (439155) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (52224400) PubChem (5284331) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (71170554) PubChem (13231890) PubChem (164157219) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 4 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 91 | Chemie (HOH) |
Sequence modifications
A: 400 - 689 (UniProt: Q7L2J0)
| PDB | External Database | Details |
|---|---|---|
| Met 381 | - | expression tag |
| Gly 382 | - | expression tag |
| Ser 383 | - | expression tag |
| Ser 384 | - | expression tag |
| His 385 | - | expression tag |
| His 386 | - | expression tag |
| His 387 | - | expression tag |
| His 388 | - | expression tag |
| His 389 | - | expression tag |
| His 390 | - | expression tag |
| Ser 391 | - | expression tag |
| Ser 392 | - | expression tag |
| Gly 393 | - | expression tag |
| Leu 394 | - | expression tag |
| Val 395 | - | expression tag |
| Pro 396 | - | expression tag |
| Arg 397 | - | expression tag |
| Gly 398 | - | expression tag |
| Ser 399 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46846.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 480.5 | |
| All* | Total formula weight | 47327.1 |
