6DBH

Crystal structure of PPAR gamma in complex with NMP422

Summary for 6DBH

• Entry DOI: 10.2210/pdb6dbh/pdb
• Descriptor: Peroxisome proliferator-activated receptor gamma, 4-{2-[(2,3-dioxo-1-pentyl-2,3-dihydro-1H-indol-5-yl)sulfanyl]ethyl}benzoic acid, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: nuclear receptor, transcription factor, super agonist, ligand binding domain, coactivator, med1, dna binding protein, dna binding protein-agonist complex, dna binding protein/agonist
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 69206.17

Authors

Mou, T.C.,Chrisman, I.M.,Hughes, T.S.,Sprang, S.R. (deposition date: 2018-05-03, release date: 2019-05-08, Last modification date: 2023-10-04)

• Primary citation: Mou, T.C.,Chrisman, I.M.,Hughes, T.S.,Sprang, S.R.; Crystal structure of PPAR gamma in complex with NMP422; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.597 Å)