6D7T
Cryo-EM structure of human TRPV6-Y467A in complex with 2-Aminoethoxydiphenyl borate (2-APB)
Summary for 6D7T
Entry DOI | 10.2210/pdb6d7t/pdb |
EMDB information | 7825 |
Descriptor | Transient receptor potential cation channel subfamily V member 6, 2-aminoethyl diphenylborinate, CALCIUM ION (3 entities in total) |
Functional Keywords | ion channels, transporter, calcium channel, epithelial calcium channel, membrane protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 341287.97 |
Authors | Singh, A.K.,Saotome, K.,McGoldrick, L.L.,Sobolevsky, A.I. (deposition date: 2018-04-25, release date: 2018-07-18, Last modification date: 2019-12-18) |
Primary citation | Singh, A.K.,Saotome, K.,McGoldrick, L.L.,Sobolevsky, A.I. Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB. Nat Commun, 9:2465-2465, 2018 Cited by PubMed: 29941865DOI: 10.1038/s41467-018-04828-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.44 Å) |
Structure validation
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