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6D6L

The structure of ligand binding domain of LasR in complex with TP-1 homolog, compound 14

Summary for 6D6L
Entry DOI10.2210/pdb6d6l/pdb
Related6D6A 6D6B 6D6C 6D6D
DescriptorTranscriptional activator protein LasR, 2,4-dibromo-6-{[(2-nitrobenzene-1-carbonyl)amino]methyl}phenyl 4-chlorobenzoate (3 entities in total)
Functional Keywordsluxr receptor, signaling protein, signaling protein-agonist complex, signaling protein/agonist
Biological sourcePseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Total number of polymer chains4
Total formula weight78308.27
Authors
Dong, S.H.,Nair, S.K. (deposition date: 2018-04-21, release date: 2018-08-08, Last modification date: 2024-03-13)
Primary citationO'Reilly, M.C.,Dong, S.H.,Rossi, F.M.,Karlen, K.M.,Kumar, R.S.,Nair, S.K.,Blackwell, H.E.
Structural and Biochemical Studies of Non-native Agonists of the LasR Quorum-Sensing Receptor Reveal an L3 Loop "Out" Conformation for LasR.
Cell Chem Biol, 25:1128-1139.e3, 2018
Cited by
PubMed: 30033130
DOI: 10.1016/j.chembiol.2018.06.007
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.63 Å)
Structure validation

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