6D36
Structure of human ARH3 bound to ADP-ribose and magnesium
Summary for 6D36
Entry DOI | 10.2210/pdb6d36/pdb |
Descriptor | Poly(ADP-ribose) glycohydrolase ARH3, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | poly(adp-ribose) hydrolase, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 159543.55 |
Authors | Pourfarjam, Y.,Ventura, J.,Kurinov, I.,Kim, I.K. (deposition date: 2018-04-14, release date: 2018-06-20, Last modification date: 2023-10-04) |
Primary citation | Pourfarjam, Y.,Ventura, J.,Kurinov, I.,Cho, A.,Moss, J.,Kim, I.K. Structure of human ADP-ribosyl-acceptor hydrolase 3 bound to ADP-ribose reveals a conformational switch that enables specific substrate recognition. J.Biol.Chem., 293:12350-12359, 2018 Cited by PubMed: 29907568DOI: 10.1074/jbc.RA118.003586 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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