6D08
Crystal structure of an engineered bump-hole complex of mutant human chromobox homolog 1 (CBX1) with H3K9bn peptide
Summary for 6D08
Entry DOI | 10.2210/pdb6d08/pdb |
Descriptor | Chromobox protein homolog 1, Histone H3.1, GLYCEROL, ... (5 entities in total) |
Functional Keywords | lysine modification, chromodomain, bump-hole, epigenetics, protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 16646.63 |
Authors | Arora, S.,Horne, W.S.,Islam, K. (deposition date: 2018-04-10, release date: 2019-04-10, Last modification date: 2023-11-15) |
Primary citation | Arora, S.,Horne, W.S.,Islam, K. Engineering Methyllysine Writers and Readers for Allele-Specific Regulation of Protein-Protein Interactions. J.Am.Chem.Soc., 141:15466-15470, 2019 Cited by PubMed: 31518125DOI: 10.1021/jacs.9b05725 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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